反应条件
1.1: InI / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N,N',N',N'',N''-hexamethylphosphoric triamide; tetrahydrofuran / 1 h / 0 °C 2.1: trifluoroacetic acid / 48 h / 25 °C 3.1: 2,2,6,6-tetramethylpiperidinyl-lithium / tetrahydrofuran / 0.5 h / -78 °C 3.2: 6.5 h / -78 - 0 °C 4.1: (-)-Ipc2BH / tetrahydrofuran / 2 h / 0 °C 4.2: 1 h / 0 - 20 °C 5.1: lithium hydroxide hydrate / methanol / 24 h / 45 °C 5.2: pH 4 6.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 0.17 h / 0 °C 7.1: chloroformic acid ethyl ester; triethylamine / dichloromethane / 2 h / 0 °C 7.2: 2.5 h / 0 - 20 °C 8.1: cesium fluoride; methanol / 3 h / 20 °C View Scheme
