1-(氯甲基)-4-硝基苯合成路线 （共 349 条）
反应条件
nickel in ethylene glycol dimethyl ether 1 h; Ambient temperature;
参考文献
Inaba, Shin-ichi; Matsumoto, Hideyuki; Rieke, Reuben D.
Journal of Organic Chemistry, 1984 , vol. 49, # 12 p. 2093 - 2098
反应条件
tetrakis(dimethylamino)ethylene in N,N-dimethyl-formamide T=-20 - 20°C; 3 h; Inert atmosphere;
参考文献
Synthesis, , # 5 art. no. Z22109SS, p. 844 - 848
反应条件
potassium hydroxide T=28°C; 2.5 h; Further byproducts given;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 2 p. 147 - 150
反应条件
potassium tert-butylate in dichloromethane Mechanism;
参考文献
Chhaly, Leang; Pritzkow, Wilhelm
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1994 , vol. 336, # 6 p. 558 - 560
反应条件
1: ethanol 2: concentrated aqueous HBr View Scheme
参考文献
Schloegl et al.
Monatshefte fuer Chemie, 1952 , vol. 83, p. 845,861
反应条件
hydrogenchloride; potassium carbonate; tetrabutylammomium bromide 1.) acetonitrile, 1 h, reflux, 2.) ether, 3 h, 3.) reflux, 6 h; Yield given. Multistep reaction;
参考文献
O'Donnell, Martin J.; Wojciechowski, Krzysztof; Ghosez, Leon; Navarro, Mirtha; Sainte, Francy; Antoine, Jean-Pierre
Synthesis, 1984 , # 4 p. 313 - 315
参考文献
Weisler; Helmkamp
Journal of the American Chemical Society, 1945 , vol. 67, p. 1167,1169
反应条件
N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide in water; dimethyl sulfoxide 1 h; Cooling with ice; Overall yield = 15 percent; Overall yield = 0.42 g;
参考文献
Zyuzin
Russian Journal of Organic Chemistry, 2013 , vol. 49, # 5 p. 678 - 685
Zh. Org. Khim., 2013 , vol. 49, # 5 p. 697 - 703,7
反应条件
potassium hydroxide in water T=50°C; 3 h; Green chemistry;
参考文献
Chen, Wen-Xin; Zhang, Cai-Yun; Shao, Li-Xiong
Tetrahedron, 2014 , vol. 70, # 4 p. 880 - 885
反应条件
in tetrahydrofuran T=20°C; benzylation;
参考文献
Shiraishi, Mitsuru; Aramaki, Yoshio; Seto, Masaki; Imoto, Hiroshi; Nishikawa, Youichi; Kanzaki, Naoyuki; Okamoto, Mika; Sawada, Hidekazu; Nishimura, Osamu; Baba, Masanori; Fujino, Masahiko
Journal of Medicinal Chemistry, 2000 , vol. 43, # 10 p. 2049 - 2063
