1-(氯甲基)-4-硝基苯合成路线 （共 349 条）
参考文献
Bergmann; Hervey
Chemische Berichte, 1929 , vol. 62, p. 915
参考文献
Fichter; Wortsmann
Chemische Berichte, 1904 , vol. 37, p. 1992
参考文献
Barrow; Griffiths
Journal of the Chemical Society, 1921 , vol. 119, p. 216
反应条件
potassium hydroxide; hydrazine hydrate; diethylene glycol
参考文献
Huang-Minlon
Journal of the American Chemical Society, 1948 , vol. 70, p. 2802,2804
反应条件
pyridine; tri-n-butyltin bromide T=50°C; Δ G; Thermodynamic dataEquilibrium constant;
参考文献
Journal of the American Chemical Society, , vol. 102, # 4 p. 1367 - 1371
反应条件
1: 99 percent / tetrahydrofuran / 20 °C 2: 43 percent / H2 / 10percent Pd/C / ethyl acetate / 2 h / 20 °C View Scheme
参考文献
Biagi; Dell'Omodarme; Ferretti; Giorgi; Livi; Scartoni
Farmaco, 1992 , vol. 47, # 3 p. 335 - 344
反应条件
1: 61 percent / K2CO3 / butan-2-one / 46 h / Heating 2: 95 percent / H2 / 5percent Pd/C / aq. ethanol / 760 Torr / Ambient temperature View Scheme
参考文献
Biagi; Dell'Omodarme; Ferretti; Giorgi; Livi; Scartoni
Farmaco, 1992 , vol. 47, # 3 p. 335 - 344
反应条件
sodium iodide in acetone 1 h; Heating / reflux;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: WO2004/96796 A1, 2004 ;
Location in patent: Page 36 ;
WO 2004/096796 A1
参考文献
Kumpf
Justus Liebigs Annalen der Chemie, 1884 , vol. 224, p. 126
参考文献
Busch; Lang
Journal fuer Praktische Chemie (Leipzig), 1936 , vol. <2> 144, p. 291,305
