1-(氯甲基)-4-硝基苯合成路线 （共 349 条）
反应条件
1: 5 h / 140 °C
2: sodium hydride / tetrahydrofuran / 0.5 h / 50 °C / |Inert atmosphere
3: hydrogenchloride; SnCl2·2H2O / ethanol; water / 7 h / 20 °C / |Reflux
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参考文献
Fang, Zhengjun; Cao, Chenzhong; Chen, Guanfan
Journal of Physical Organic Chemistry, 2012 , vol. 25, # 12 p. 1343 - 1350
反应条件
ethanol; sodium iodide
und Einleiten von Chlorwasserstoff in das Reaktionsgemisch;
参考文献
Galat; Elion
Journal of the American Chemical Society, 1939 , vol. 61, p. 3586
参考文献
Ji, Pengju; Atherton, John; Page, Michael I.
Journal of Organic Chemistry, 2011 , vol. 76, # 5 p. 1425 - 1435
反应条件
und Spaltung des entstandenen N-<4-Nitro-benzyl>-phthalimids mit rauch.Salzsaeure bei 190-200grad;
参考文献
Salkowski
Chemische Berichte, 1889 , vol. 22, p. 2142
反应条件
sodium hydroxide; Aliquatreg; 336 in hexane; water
10 h; Heating; Yield given. Yields of byproduct given;
参考文献
Shinkai, I.; Zwan, M. C. Vander; Hartner, F. W.; Reamer, R. A.; Tull, R. J.; Weinstock, L. M.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 197 - 198
反应条件
sodium hydride
1.) DMF, 30 deg C, 1 h, 2.) DMF, 16 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Rasmussen, Malcolm; Hope, Janet M.
Australian Journal of Chemistry, 1982 , vol. 35, # 3 p. 525 - 534
反应条件
potassium ethanolate
1.) EtOH, 2.) DMF, 30 deg C, 16 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Rasmussen, Malcolm; Hope, Janet M.
Australian Journal of Chemistry, 1982 , vol. 35, # 3 p. 535 - 542
参考文献
Schoenberg; Iskander
Journal of the Chemical Society, 1942 , p. 90,92
参考文献
Curtius
Journal fuer Praktische Chemie (Leipzig), 1930 , vol. <2> 125, p. 211,284
参考文献
Lellmann; Schleich
Chemische Berichte, 1887 , vol. 20, p. 441
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Reissert
Chemische Berichte, 1894 , vol. 27, p. 2248
