1-(氯甲基)-4-硝基苯合成路线 （共 349 条）
反应条件
Ambient temperature;
参考文献
Huang, Yue; Turecek, Frantisek; Yoon, Sung Hwan; Heron, Scott R.; Masselon, Christophe D.; Edgar, J. Scott; Goodlett, David R.
Journal of the American Society for Mass Spectrometry, 2012 , vol. 23, # 6 p. 1062 - 1070,9
反应条件
in ethanol
T=95°C; 2 h;
参考文献
Barker, Courtney A.; Allison, Sarah E.; Zlitni, Soumaya; Nguyen, Nick Duc; Das, Rahul; Melacini, Giuseppe; Capretta, Alfredo A.; Brown, Eric D.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 8 p. 2426 - 2431
反应条件
1: K2CO3; H2O
View Scheme
参考文献
Kochi; Hammond
Journal of the American Chemical Society, 1953 , vol. 75, p. 3452,3453
参考文献
Niyogy
Journal of the Indian Chemical Society, 1930 , vol. 7, p. 577,583
反应条件
3: tin dichloride; concentrated hydrochloric acid; alcohol
View Scheme
参考文献
Montagne
Chemische Berichte, 1916 , vol. 49, p. 2274
反应条件
ethanol; sodium carbonate
参考文献
Behrend; Leuchs
Justus Liebigs Annalen der Chemie, 1890 , vol. 257, p. 239
反应条件
1: 74 percent / Na, EtOH / 12 h / Heating
2: 1.) H2, 2.) HCl / 1.) 10percent Pd/C / 1.) ethanol, 8 h, reflux
3: 82 percent / NaNO2, 37percent HCl / methanol; H2O / 1.) 5 deg C - room temp., 2.) 3 h, reflux
View Scheme
参考文献
Leclerc; Decker; Schwartz
Arzneimittel-Forschung/Drug Research, 1985 , vol. 35, # 9 p. 1357 - 1367
反应条件
nitromethane; silver perchlorate; magnesium oxide
参考文献
Praill
Journal of the Chemical Society, 1957 , p. 3162
反应条件
in dimethyl sulfoxide
T=100°C; 22 h;
参考文献
Duke University
Patent: US2010/94060 A1, 2010 ;
Location in patent: Page/Page column 5 ;
反应条件
in dimethyl sulfoxide; nitrobenzene
T=40°C; Rate constant;
参考文献
Litvinenko, L. M.; Shpan'ko, I. V.; Korostylev, A. P.
Doklady Chemistry, 1982 , vol. 266, p. 309 - 313
Dokl. Akad. Nauk SSSR Ser. Khim., 1982 , vol. 266, # 1 p. 131 - 134
