1-(氯甲基)-4-硝基苯合成路线 (共 349 条)
反应条件
potassium hydroxide; phenol
参考文献
Kumpf
Justus Liebigs Annalen der Chemie, 1884 , vol. 224, p. 126
反应条件
15-crown-5 in methanol T=20°C; α-deuterium kinetic isotope effect also in the absence of crown ether; Rate constant;
参考文献
Fang, Yao-Ren; Lai, Zhu-Gen; Westaway, Kenneth Charles
Canadian Journal of Chemistry, 1998 , vol. 76, # 6 p. 758 - 764
反应条件
1: triethylamine; ethyl acetate 2: HBr; acetic acid 3: dicyclohexylcarbodiimide; CH2Cl2 View Scheme
参考文献
CIBA
Patent: DE1126397 , 1960 ;
参考文献
Overberger et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 2356,2359
反应条件
tetrabutylammomium bromide in sodium hydroxide; benzene 0.25 h; Ambient temperature; Yield given;
参考文献
Takido, Toshio; Itabashi, Kunio
Synthesis, 1987 , # 9 p. 817 - 819
参考文献
Stedman
Journal of the Chemical Society, 1927 , p. 1904
反应条件
ethanol Chlorid des Trimethyl-<4-nitro-benzyl>-ammoniumhydroxyds entstehen;
参考文献
Ing; Robinson
Journal of the Chemical Society, 1926 , p. 1665
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Ingold; Ingold
Journal of the Chemical Society, 1928 , p. 2262
反应条件
1: diluted alcohol; natrium carbonate 2: hydrochloric acid / 140 °C / im Druckrohr View Scheme
参考文献
Behrend; Leuchs
Justus Liebigs Annalen der Chemie, 1890 , vol. 257, p. 239
反应条件
in chloroform Ambient temperature;
参考文献
Buckley, Neil; Maltby, David; Burlingame, Alma L.; Oppenheimer, Norman J.
Journal of Organic Chemistry, 1996 , vol. 61, # 8 p. 2753 - 2762
反应条件
potassium carbonate; acetone
参考文献
Nair; Robinson
Journal of the Chemical Society, 1932 , p. 1236,1238