Strokin, Yu. V.; Zarudii, F. S.; Kremzer, A. A.; Nazinov, N. M.; Chvalyuk, N. V.; Lazareva, D. N.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 5 p. 338 - 341
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 5 p. 566 - 569
1: 1.) triethylamine / 1.) ether, -78 deg C, 2.) dichloromethane
2: 1.) n-butyl-lithium / 1.) DME, -78 deg C -> room temperature, 60 min, room temperature 30 min, 2.) -78 deg C -> room temperature 15 min
3: 1.) n-butyl-lithium, 2.) toluene-4-sulphonic anhydride / 1.) THF, -78 deg C -> 0 deg C, 2.) -78 deg C -> room temperature
View Scheme
参考文献
Adlington, Robert M.; Barrett, Anthony G.M.; Quayle, Peter; Walker, Andrew; Betts, Michael J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 605 - 612
1: 82 percent / DCC / CH2Cl2 / 20 °C
2: 94 percent / Et3N / CH2Cl2 / 0 °C
3: 46 percent / tBuOK / tetrahydrofuran / 2 h / -15 °C
View Scheme
参考文献
Adlington, Robert M.; Barrett, Anthony G.M.; Quayle, Peter; Walker, Andrew; Betts, Michael J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 605 - 612
