1: ortho-fluorobromobenzene With magnesium in tetrahydrofuran
Inert atmosphere;
2: 2-pyridine carbonitrile in tetrahydrofuran
T=0°C; Inert atmosphere;
3: With hydrogenchloride; water in diethyl ether
0.5 h; Inert atmosphere;
1: diethyl ether / anschliessenden Behandeln des Reaktionsgemisches mit wss.Ammoniumchlorid-Loesung
2: aqueous ethanol
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参考文献
Teague et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 3429
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Henze; Knowles
Journal of Organic Chemistry, 1954 , vol. 19, p. 1127,1129
1: 1-bromo-2-methyl benzene With magnesium in tetrahydrofuran
Inert atmosphere;
2: 2-pyridine carbonitrile in tetrahydrofuran
T=0°C; Inert atmosphere;
3: With hydrogenchloride; water in diethyl ether
0.5 h; Inert atmosphere;