2-甲酰基-3,4-二氢吡喃合成路线 （共 35 条）
反应条件
1: 1) DIBAH; 2) NH4Cl / diethyl ether; H2O / 2 h
2: TsOH / 12 h / Ambient temperature
3: pyridine chlorochromate, CH3COONa / CH2Cl2
4: H(+), CH3CO2H, H2O
View Scheme
参考文献
Leggeri; Azzolina; Pirillo; Traverso
Farmaco, 1989 , vol. 44, # 3 p. 303 - 313
反应条件
silver(l) oxide; benzene
Erwaermen des Reaktionsprodukts mit Benzol und Aethyljodid;
参考文献
Whetstone; Ballard
Journal of the American Chemical Society, 1951 , vol. 73, p. 5280
反应条件
Raney-Co; ammonia; hydrogen in tetrahydrofuran; water
T=100°C; 2.25 h; Industry scaleCompressed gas(es)Compressed liquid(s);
参考文献
MERCK PATENT GMBH
Patent: WO2009/77052 A2, 2009 ;
Location in patent: Page/Page column 28 ;
反应条件
1: 86 percent
2: 90 percent / lithium aluminum hydride / diethyl ether / 5 h / Heating
3: 70 percent / concentrated hydrochloric acid / 1) 0 deg C, 30 min, 2) room temperature, 15 min
View Scheme
参考文献
Singh, S. M.; Singh, Sujan; Rao, R. Balaji
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 310 - 312
反应条件
benzene
Entfernen des entstehenden Wassers;
参考文献
Shell Devel. Co.
Patent: US2566815 , 1947 ;
