1: 90 percent / K2CO3 / acetonitrile / 48 h / Heating
2: 100 percent / methanol; H2O / 0 °C
3: 100 percent / NaBH4 / methanol; H2O / 18.5 h / 0 - 23 °C
View Scheme
参考文献
Deng, Xiaohu; Liang, Jimmy T.; Liu, Jing; McAllister, Heather; Schubert, Garsten; Mani, Neelakandha S.
Organic Process Research and Development, 2007 , vol. 11, # 6 p. 1043 - 1050
1: 90 percent / K2CO3 / acetonitrile / 48 h / Heating
2: 100 percent / methanol; H2O / 0 °C
3: 100 percent / NaBH4 / methanol; H2O / 18.5 h / 0 - 23 °C
4: (i-Pr)2NEt / tetrahydrofuran / 0.75 h / 23 °C
View Scheme
参考文献
Deng, Xiaohu; Liang, Jimmy T.; Liu, Jing; McAllister, Heather; Schubert, Garsten; Mani, Neelakandha S.
Organic Process Research and Development, 2007 , vol. 11, # 6 p. 1043 - 1050
1: 90 percent / K2CO3 / acetonitrile / 48 h / Heating
2: 100 percent / methanol; H2O / 0 °C
3: 100 percent / NaBH4 / methanol; H2O / 18.5 h / 0 - 23 °C
4: (i-Pr)2NEt / tetrahydrofuran / 0.75 h / 23 °C
5: methanesulfonic acid / 18 h / 60 °C
6: NaCNBH3 / methanol / 0.08 h / 23 °C
View Scheme
参考文献
Deng, Xiaohu; Liang, Jimmy T.; Liu, Jing; McAllister, Heather; Schubert, Garsten; Mani, Neelakandha S.
Organic Process Research and Development, 2007 , vol. 11, # 6 p. 1043 - 1050
1: potassium carbonate / acetonitrile / 3 h / 20 °C / |Reflux
2: ethanol; water / 0.33 h / 0 °C
3: sodium tetrahydroborate / 3 h / 0 °C
4: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.33 h / 20 °C
5: sodium tetrahydroborate / water; methanol / 2 h / 0 - 20 °C
6: methanesulfonic acid / dichloromethane / 2 h / 20 °C / |Inert atmosphere; |Cooling with ice
View Scheme
参考文献
Deng, Xiaohu; Liang, Jimmy T.; Liu, Jing; McAllister, Heather; Schubert, Garsten; Mani, Neelakandha S.
Organic Process Research and Development, 2007 , vol. 11, # 6 p. 1043 - 1050
