(吡啶-2-基磺酰基)乙酸合成路线 （共 6 条）
反应条件
1: With methanol; sodium hydroxide; water T=20°C; 0.75 h; 2: Acidic aqueous solution;
参考文献
ANORMED INC.
Patent: WO2006/138350 A2, 2006 ;
Location in patent: Page/Page column 72 ;
WO 2006/138350 A2
反应条件
triethylamine in dichloromethane T=0 - 20°C; 48 h;
参考文献
Otto, Nicola; Opatz, Till
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 1105 - 1111
反应条件
water; chloroacetic acid
参考文献
Chemische Berichte, , vol. 33, p. 1556
参考文献
Chemische Berichte, , vol. 66, p. 364,368
反应条件
in acetic anhydride
(heating);
参考文献
Gorb,L.T. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1979 , vol. 15, p. 1081 - 1085
Khimiya Geterotsiklicheskikh Soedinenii, 1979 , vol. 15, p. 1343 - 1347
反应条件
Ni(PPh2Me)2Cl2 in tetrahydrofuran
T=50°C; cross-coupling; 14 h;
参考文献
Srogl, Jiri; Liu, Wansheng; Marshall, Daniel; Liebeskind, Lanny S.
Journal of the American Chemical Society, 1999 , vol. 121, # 40 p. 9449 - 9450
