2-氨基-5-溴吡啶-4-羧酸合成路线 （共 2 条）
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran; methanol T=70°C; 2 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; methanol; water T=0°C; pH=6;
参考文献
PRESIDIO PHARMACEUTICALS, INC.; ZHONG, Min; LI, Leping
Patent: WO2012/58125 A1, 2012 ;
Location in patent: Page/Page column 145 ;
WO 2012/058125 A1
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran; methanol
T=70°C; 2 h; Inert atmosphere;
2: With hydrogenchloride in tetrahydrofuran; methanol; water
T=0°C; pH=6;
参考文献
PRESIDIO PHARMACEUTICALS, INC.; ZHONG, Min; LI, Leping
Patent: WO2012/58125 A1, 2012 ;
Location in patent: Page/Page column 145 ;
WO 2012/058125 A1
