6-氯-5-氮杂吲哚-3-羧酸合成路线 （共 2 条）
反应条件
1: C10H13ClN2Si With tetrabutyl ammonium fluoride in tetrahydrofuran Reflux; 2: trifluoroacetic acid With water; sodium hydroxide in tetrahydrofuran T=0°C; 14 h;
参考文献
FENG, Yangbo; CHEN, Yen Ting; SESSIONS, Hampton; MISHRA, Jitendra K.; CHOWDHURY, Sarwat; YIN, Yan; LOGRASSO, Philip; LUO, Jun-Li; BANNISTER, Thomas; SCHROETER, Thomas
Patent: WO2011/50245 A1, 2011 ;
Location in patent: Page/Page column 146 ;
WO 2011/050245 A1
反应条件
1.1: triethylamine; copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 1 h / 150 °C 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / Reflux 2.2: 14 h / 0 °C View Scheme
参考文献
FENG, Yangbo; CHEN, Yen Ting; SESSIONS, Hampton; MISHRA, Jitendra K.; CHOWDHURY, Sarwat; YIN, Yan; LOGRASSO, Philip; LUO, Jun-Li; BANNISTER, Thomas; SCHROETER, Thomas
Patent: WO2011/50245 A1, 2011 ;
WO 2011/050245 A1
