(R)-(+)-2-溴丙酸合成路线 (共 21 条)
反应条件
hydrogen bromide; potassium bromide; sodium nitrite T=0 - 5°C; 1 h;
参考文献
Archer, Catherine H.; Thomas, Neil R.; Gani, David
Tetrahedron: Asymmetry, 1993 , vol. 4, # 6 p. 1141 - 1152
反应条件
1: With lithium bromide in toluene T=60°C; 1 h; 2: in water; toluene T=20°C; 0.5 h;
参考文献
KANEKA CORPORATION
Patent: EP1422215 A1, 2004 ;
Location in patent: Page 23 ;
参考文献
Chemische Berichte, , vol. 40, p. 491
Chemische Berichte, , vol. 39, p. 3988
Chem. Zentralbl., , vol. 77, # II p. 60
反应条件
1: With n-butyllithium; diethylzinc; (S)-(+)-3-hydroxy-tetrahydrofuran in hexane; toluene T=-78 - 0°C; 13 h; 2: With hydrogenchloride in tetrahydrofuran T=20°C; 48 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 42, # 34 p. 5985 - 5987
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran 0.5 h; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron: Asymmetry, , vol. 6, # 8 p. 1919 - 1932
参考文献
Journal of the Chemical Society, , p. 1228
参考文献
Bulletin des Societes Chimiques Belges, , vol. 46, p. 485
参考文献
Chemische Berichte, , vol. 33, p. 3355
Justus Liebigs Annalen der Chemie, , vol. 349, p. 325
参考文献
Justus Liebigs Annalen der Chemie, , vol. 370, p. 236,237
Justus Liebigs Annalen der Chemie, , vol. 340, p. 171
Justus Liebigs Annalen der Chemie, , vol. 349, p. 325
Chemische Berichte, , vol. 33, p. 3354
参考文献
Chemische Berichte, , vol. 28, p. 1295,1296
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 30, p. 535,538