反应条件
1: N-[[2'-(1-triphenylmethyltetrazol-5-yl)biphenyl-4-yl]methyl]valine methyl ester oxalate With sodium carbonate in water; toluene
T=20 - 30°C;
2: n-valeryl chloride With N-ethyl-N,N-diisopropylamine in toluene
T=0 - 10°C;
参考文献
Kumar N, Senthil; Reddy, Shankar B.; Sinha, Brajesh Kumar; Mukkanti, Kagga; Dandala, Ramesh
Organic Process Research and Development, 2009 , vol. 13, # 6 p. 1185 - 1189