(2S)-2-呋喃基(羟基)乙腈合成路线 （共 12 条）
反应条件
1: 1.) isopropenyl acetate, 2.) imidazole / 1.) i-Pr2O, lipase, 40 deg C, 47 h, 2.) i-Pr2O, DMF, RT, overnight 2: HCl conc. / acetic acid; H2O / 3 h / 40 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 65, # 1 p. 111 - 120
反应条件
phosphate buffer; 2-hydroxy-1,2,3-propanetricarboxylate; Aqua Gel matrix; hydroxynitrile lyase from Prunus amygdalus (EC 4.1.2.10) in di-isopropyl ether T=20°C; pH=5.0; 72 h; KineticsProduct distribution; Further Variations:Reagentssingle phase reaction, without support, reaction time;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 12-13 p. 1645 - 1654
