1-(1H-吲唑-5-基)乙酮合成路线 （共 5 条）
反应条件
1: With hydrogenchloride; water in methanol T=50°C; 8.5 h; 2: With sodium carbonate in methanol; water pH=10;
参考文献
WO2009/89057 A1, ;
Page/Page column 52-53 ;
WO 2009/089057 A1
反应条件
1: With hydrogenchloride; water in tetrahydrofuran 25 h; 2: With sodium carbonate in water; ethyl acetate
参考文献
WO2008/7211 A1, ;
Page/Page column 42 ;
WO 2008/007211 A1
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane; N,N-dimethyl-formamide / 24 h / 20 °C 2: tetrahydrofuran / 0 - 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1480 - 1483
反应条件
in tetrahydrofuran T=0 - 20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1480 - 1483
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane
T=20°C;
参考文献
Akritopoulou-Zanze, Irini; Wakefield, Brian D.; Gasiecki, Alan; Kalvin, Douglas; Johnson, Eric F.; Kovar, Peter; Djuric, Stevan W.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 5 p. 1480 - 1483
