(R)-(+)-苯乙醇腈合成路线 （共 51 条）
参考文献
Justus Liebigs Annalen der Chemie, , vol. 510, p. 230,239
Chemische Berichte, , vol. 64, p. 427,432
反应条件
yeast lipase; butan-1-ol in di-isopropyl ether T=30°C; 48 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 54, # 10 p. 2453 - 2455
反应条件
in di-isopropyl ether T=5°C; 23 h; almond meal oxynitrilase, 0.1 M tartrate buffer, pH 5.4;
参考文献
Kiljunen, Eero; Kanerva, Liisa T.
Tetrahedron Asymmetry, 1996 , vol. 7, # 4 p. 1105 - 1116
反应条件
R-selective hydroxynitrile lyase from Prunus amygdalus in phosphate buffer; toluene T=20°C; pH=7.0; 24 h;
参考文献
Purkarthofer, Thomas; Skranc, Wolfgang; Weber, Hansjoerg; Griengl, Herfried; Wubbolts, Marcel; Scholz, Gerald; Poechlauer, Peter
Tetrahedron, 2004 , vol. 60, # 3 p. 735 - 739
反应条件
1: With (S,S)-(salen derivative)titanium in dichloromethane; water; tert-butyl alcohol T=-40°C; 2: With candida antarctica lipase-B; isopropyl alcohol in various solvents T=20°C; 7 h;
参考文献
European Journal of Organic Chemistry, , # 20 p. 4609 - 4617
反应条件
1: CH3P(O)Ph2 / Me2AlCl/[(R)-3,3'-bis(Ph2P(=O)CH2)-1,1'-bi(2-naphthol)] / CH2Cl2 / 96 h / -40 °C 2: aq. HCl / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 57, # 5 p. 805 - 814
反应条件
buffer ( pH=5.4 ); oxynitralase in ethanol; acetic acid T=0°C; 0.666667 h; Yield given;
参考文献
Tetrahedron Letters, , vol. 29, # 35 p. 4485 - 4488
反应条件
sodium acetate; acetic acid 4.5 h; Ambient temperaturePseudomonas fluorescens lipase, pH 4.5; Title compound not separated from byproducts;
参考文献
Effenberger, Franz; Gutterer, Beate; Ziegler, Thomas; Eckhardt, Elisabeth; Aichholz, Reiner
Liebigs Annalen der Chemie, 1991 , # 1 p. 47 - 54
反应条件
hydrogen fluoride in acetonitrile T=45°C;
参考文献
Tetrahedron, , vol. 46, # 3 p. 979 - 986
反应条件
hydrogenchloride Ambient temperature; Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 9 p. 1293 - 1295
