2,3,4,5-四氟-alpha-[(2-甲酰基-2-甲基肼基)亚甲基]-beta-氧代苯丙酸乙酯合成路线 (共 3 条)
反应条件
formic acid; sodium carbonate in acetic acid n-butyl ester; water; ethyl acetate
参考文献
Pfizer. Inc
Patent: US5892040 A1, 1999 ;
反应条件
in dichloromethane; tert.-butyl-methyl ether; water; toluene
参考文献
Pfizer. Inc
Patent: US5892040 A1, 1999 ;
反应条件
With NAF in N,N-dimethyl-formamide T=140 - 150°C; 2 h;
参考文献
Grohe, Klaus; Heitzer, Helmut Liebigs Annalen der Chemie, 1987 , p. 871 - 880