四氢硫代吡喃-4-基甲醇合成路线 （共 14 条）
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran T=70°C; 2.25 h; 2: With water in tetrahydrofuran T=20°C;
参考文献
WO2007/6732 A1, ;
Page/Page column 8 ;
WO 2007/006732 A1
参考文献
Justus Liebigs Annalen der Chemie, , vol. 537, p. 214,217
反应条件
lithium aluminium tetrahydride in diethyl ether 4 h; Heating;
参考文献
Mori, Mitsuo; Takeuchi, Hiroyuki; Minato, Hiroshi; Kobayashi, Michio; Yoshida, Masato; et al.
Phosphorus, Sulfur and Silicon and the Related Elements, 1990 , vol. 47, # 1 + 2 p. 157 - 164
反应条件
1: potassium tert-butylate / ethylene glycol dimethyl ether; tert-butyl alcohol / 3 h / 0 - 20 °C 2: water; sodium hydroxide / ethanol / 2 h / 90 °C 3: dimethylsulfide borane complex / tetrahydrofuran / 2 h / 70 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 6 p. 1748 - 1753
反应条件
1: 69 percent / 48percent aq. HBr, HBr gas / 12 h / 100 °C 2: 69 percent / PBr3 / 1 h / Heating 3: 68 percent / diethyl ether 4: 41 percent / aq. Na2S / ethanol / 2 h / Heating 5: 60 percent / LiAlH4 / diethyl ether / 4 h / Heating View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 47, # 1 + 2 p. 157 - 164
反应条件
1: 75 percent / 171 °C 2: 69 percent / 48percent aq. HBr, HBr gas / 12 h / 100 °C 3: 69 percent / PBr3 / 1 h / Heating 4: 68 percent / diethyl ether 5: 41 percent / aq. Na2S / ethanol / 2 h / Heating 6: 60 percent / LiAlH4 / diethyl ether / 4 h / Heating View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 47, # 1 + 2 p. 157 - 164
反应条件
1: 68 percent / diethyl ether 2: 41 percent / aq. Na2S / ethanol / 2 h / Heating 3: 60 percent / LiAlH4 / diethyl ether / 4 h / Heating View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 47, # 1 + 2 p. 157 - 164
反应条件
1: 88 percent / 10percent aq. HCl / Heating 2: 75 percent / 171 °C 3: 69 percent / 48percent aq. HBr, HBr gas / 12 h / 100 °C 4: 69 percent / PBr3 / 1 h / Heating 5: 68 percent / diethyl ether 6: 41 percent / aq. Na2S / ethanol / 2 h / Heating 7: 60 percent / LiAlH4 / diethyl ether / 4 h / Heating View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 47, # 1 + 2 p. 157 - 164
反应条件
1: 69 percent / PBr3 / 1 h / Heating 2: 68 percent / diethyl ether 3: 41 percent / aq. Na2S / ethanol / 2 h / Heating 4: 60 percent / LiAlH4 / diethyl ether / 4 h / Heating View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 47, # 1 + 2 p. 157 - 164
反应条件
1: 41 percent / aq. Na2S / ethanol / 2 h / Heating 2: 60 percent / LiAlH4 / diethyl ether / 4 h / Heating View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 47, # 1 + 2 p. 157 - 164
