1: 2-(N,N-diphenylamino)thiophene With n-butyllithium in tetrahydrofuran; hexane
T=-70 - 20°C;
2: With tributyltin chloride in tetrahydrofuran; hexane
3: thien-2-yl bromide With tetrakis(triphenylphosphine) palladium(0) in toluene
T=80°C; 8 h;
(i) Mg, Et2O, (ii) /BRN= 473684/; Multistep reaction;
参考文献
Mikhlina,E.E. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1976 , vol. 12, p. 776 - 780
Khimiya Geterotsiklicheskikh Soedinenii, 1976 , vol. 12, p. 935 - 939