反应条件
1: 90 percent / pyridine / 0.33 h / 0 °C
2: 1.) t-BuLi, ZnCl2, 2.) LiCl, Pd(PPh3)4 / 1.) THF, pentane, -78 deg C, 30 min, 25 deg C, 2 h, 2.) reflux, 15 h
3: 99 percent / LDA / tetrahydrofuran / 1 h / -78 °C
4: 98 percent / CsF / dimethylformamide / 3 h / 25 °C
View Scheme
参考文献
Savage, Scott A.; Smith, Adam P.; Fraser, Cassandra L.
Journal of Organic Chemistry, 1998 , vol. 63, # 26 p. 10048 - 10051
