(R)-(+)-3-氯-1-苯基-1-丙醇合成路线 (共 24 条)
反应条件
borane; S-oxaborolidine in tetrahydrofuran T=0°C; 0.833333 h;
参考文献
Montalvo-Gonzalez, Ruben; Chavez, Daniel; Aguirre, Gerardo; Parra-Hakea, Miguel; Somanathan, Ratnasamy
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 3 p. 431 - 435
反应条件
dimethylsulfide borane complex; (+)-3-exo-amino-7,7-dimethoxynorbornan-2-exo-ol in tetrahydrofuran T=25°C; 2 h;
参考文献
Lapis, Alexandre A. M.; De Fatima, Angelo; Martins, Jose E. D.; Costa, Valentim E. U.; Pilli, Ronaldo A.
Tetrahedron Letters, 2005 , vol. 46, # 3 p. 495 - 498
反应条件
Pseudomonas cepacia lipase immobilized on toyonite; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl in toluene T=25°C; 168 h;
参考文献
Choi, Jun Ho; Choi, Yoon Kyung; Kim, Yu Hwan; Park, Eun Sil; Kim, Eun Jung; Kim, Mahn-Joo; Park, Jaiwook
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 1972 - 1977
反应条件
yeast strain Aureobasidium pullulans CQA T=28°C; 48 h; Microbiological reactionEnzymatic reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 102, p. 94 - 98
反应条件
Bacillus subtilis esterase in ethanol T=30°C; pH=7.2; 12 h; aq. phosphate buffer; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 3 p. 405 - 414
反应条件
lipase from Pseudomonas fluorescens in hexane T=20°C; 21 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Pop, Laura Ancua; Czompa, Andrea; Paizs, Csaba; Toa, Monica Ioana; Vass, Elemer; Matyus, Peter; Irimie, Florin-Dan
Synthesis, 2011 , # 18 art. no. T49711SS, p. 2921 - 2928
反应条件
Merulius tremellosus ono991 in acetone T=28°C; 72 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 7 p. 1025 - 1034
反应条件
1: 93 percent / pyridine; DMAP / CH2Cl2 / 0 - 20 °C 2: aq. phosphate buffer; Novozyme 435 / 288 h / 30 °C / pH 7 View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 11 p. 1767 - 1769
反应条件
Sphingomonas paucimobilis NCIMB 8195 in water; N,N-dimethyl-formamide 120 h;
参考文献
Journal of Organic Chemistry, , vol. 66, # 19 p. 6495 - 6497
反应条件
(-)-(Sa) 4-di-n-butylaminopyridine based biaryl; triethylamine in toluene T=-95°C; 15 h; Title compound not separated from byproducts.;
参考文献
Tetrahedron, , vol. 60, # 20 p. 4513 - 4525