(S)-(-)-3-氯-1-苯基-1-丙醇合成路线 （共 28 条）
参考文献
Raju, S. Bhaskar; Chiou, Tzyy-Wen; Tai, Dar-Fu
Tetrahedron: Asymmetry, 1995 , vol. 6, # 7 p. 1519 - 1520
反应条件
lipase from Pseudomonas fluorescens in hexane T=20°C; 21 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Pop, Laura Ancua; Czompa, Andrea; Paizs, Csaba; Toa, Monica Ioana; Vass, Elemer; Matyus, Peter; Irimie, Florin-Dan
Synthesis, 2011 , # 18 art. no. T49711SS, p. 2921 - 2928
反应条件
Merulius tremellosus ono991 in acetone T=28°C; 72 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 7 p. 1025 - 1034
反应条件
(-)-(Sa) 4-di-n-butylaminopyridine based biaryl; triethylamine in toluene T=-95°C; 15 h; Title compound not separated from byproducts.;
参考文献
Tetrahedron, , vol. 60, # 20 p. 4513 - 4525
反应条件
1: pH 7, Pseudomonas sp. lipase (SAM-2) 2: K2CO3 / methanol View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 32, # 1 p. 145 - 150
反应条件
phosphate buffer; novozyme 435 T=30°C; Hydrolysis; pH=7; 288 h; Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 11 p. 1767 - 1769
反应条件
T=145 - 180°C; Gas phaseResolution of racemateInert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 3 p. 405 - 414
反应条件
Lipase PS in n-heptane 96 h; var. solvents; Product distribution;
参考文献
Raju, S. Bhaskar; Chiou, Tzyy-Wen; Tai, Dar-Fu
Tetrahedron: Asymmetry, 1995 , vol. 6, # 7 p. 1519 - 1520
反应条件
1.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide; mineral oil / 3 h / 20 °C / Inert atmosphere 2.1: sodium carbonate / hexane / 6 h / 0 °C / Inert atmosphere 2.2: 12 h / 20 °C / Inert atmosphere 3.1: caesium carbonate / tetrahydrofuran; N,N-dimethyl-formamide / 20 h / 60 °C / Inert atmosphere 4.1: palladium 10 on activated carbon; hydrogen / methanol; ethyl acetate / 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Kim, Sun Joo; Jeon, Tae Hong; Min, Im Sook; Kim, In Su; Jung, Young Hoon
Tetrahedron Letters, 2012 , vol. 53, # 28 p. 3680 - 3682
反应条件
1: 75 percent / Ph3P; DEAD / tetrahydrofuran 2: 96 percent / ethanol; H2O / 130 °C View Scheme
参考文献
Chumpradit; Kung; Panyachotipun; Prapansiri; Foulon; Brooks; Szabo; Tejani-Butt; Frazer
Journal of Medicinal Chemistry, 1992 , vol. 35, # 23 p. 4492 - 4497
