1: 68 percent / CrO3, water / acetic acid / 4 h / Ambient temperature 2: aq. KOH / 4 h / Heating View Scheme

Multi-step reaction with 5 steps 1: 74 percent / K2CO3 / dimethylformamide / 1 h / Heating2: 88 percent / POCl3 / CH2Cl2 / Ambient temperature3: 90 percent / Zn-amalgam, 4 N aq. HCl / dioxane / 2 h / Heating4: H2 / 10percent Pd/C / ethyl acetate / 0.25 h / Ambient temperature5: pyridine / 2 h / Heating  

Multi-step reaction with 4 steps 1: 88 percent / POCl3 / CH2Cl2 / Ambient temperature2: 90 percent / Zn-amalgam, 4 N aq. HCl / dioxane / 2 h / Heating3: H2 / 10percent Pd/C / ethyl acetate / 0.25 h / Ambient temperature4: pyridine / 2 h / Heating  

Multi-step reaction with 2 steps 1: H2 / 10percent Pd/C / ethyl acetate / 0.25 h / Ambient temperature2: pyridine / 2 h / Heating  

Multi-step reaction with 3 steps 1: 90 percent / Zn-amalgam, 4 N aq. HCl / dioxane / 2 h / Heating2: H2 / 10percent Pd/C / ethyl acetate / 0.25 h / Ambient temperature3: pyridine / 2 h / Heating  

With  chromium(VI) oxide; water in  acetic acid 4 h;  Ambient temperature;