双环[3.2.2]壬-3-烯-2-酮合成路线 （共 4 条）
反应条件
lithium carbonate; lithium bromide in N,N-dimethyl-formamide T=110°C; 5 h;
参考文献
Inouye, Yoshinobu; Kojima, Tsutomu; Owada, Jun; Kakisawa, Hiroshi
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 12 p. 4369 - 4376
反应条件
1: 93 percent / phenyltrimethylammonium tribromide / tetrahydrofuran / 0.5 h / 0 °C 2: 95 percent / LiBr, Li2CO3 / dimethylformamide / 5 h / 110 °C View Scheme
参考文献
Doerner, Thomas; Gleiter, Rolf; Robbins, Timothy A.; Chayangkoon, Paochai; Lightner, David A.
Journal of the American Chemical Society, 1992 , vol. 114, # 9 p. 3235 - 3241
反应条件
1: 1.18 g / BF3*Et2O / benzene / Ambient temperature 2: Raney Ni / aq. ethanol / 6 h / Heating 3: 1.) CrO3, aq. H2SO4, 2.) H2 / 1.) acetone, 5 deg C, 20 min, 2.) ethyl acetate, Pd/C 4: 100 mg / conc. H2SO4 / 0.5 h / Heating 5: N-bromosuccinimide, benzoyl peroxide / CCl4 / 1 h / 75 °C 6: 62 percent / 2 N aq. HCl / aq. ethanol / 1 h / 70 °C View Scheme
参考文献
Doerner, Thomas; Gleiter, Rolf; Robbins, Timothy A.; Chayangkoon, Paochai; Lightner, David A.
Journal of the American Chemical Society, 1992 , vol. 114, # 9 p. 3235 - 3241
反应条件
1: NBS, (PhCO)2O2 / CCl4 / Heating 2: aq. KOH / dioxane / Heating 3: MnO2 View Scheme
参考文献
Davies,J.M.; Graham,S.H.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 2040 - 2041
