4,6-二氨基-2-巰基嘧啶合成路线 （共 20 条）
参考文献
Brown
Journal of the Society of Chemical Industry, London, 1950 , vol. 69, p. 353
反应条件
sodium hydroxide in methanol T=20°C; 18 h;
参考文献
Mohebbi, Shohreh; Falcon-Perez, Juan Manuel; Gonzalez, Esperanza; Millet, Oscar; Mato, Jose Maria; Kobarfard, Farzad
Chemical and Pharmaceutical Bulletin, 2012 , vol. 60, # 1 p. 70 - 78
参考文献
Joshi, Advait A.; Viswanathan
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 10 p. 2613 - 2617
反应条件
acetic acid; sodium nitrite Erhitzen des Reaktionsprodukts mit Raney-Nickel und wss.NH3 und anschliessendes Behandeln mit NaNO2 und wss.Essigsaeure;
参考文献
Davoll
Journal of the Chemical Society, 1958 , p. 1593,1597
反应条件
triethylamine in N,N-dimethyl-formamide
T=20°C; 1 h;
参考文献
Podzigun, G. I.; Pashkurov, N. G.; Reznik, V. S.; Ivanov, B. E.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1980 , vol. 29, p. 1662 - 1665
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1980 , # 10 p. 2346 - 2349
参考文献
Bendich et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 3109,3112
参考文献
Eastman Kodak Co.
Patent: US2819965 , 1956 ;
反应条件
triethylamine in acetonitrile
T=80°C;
参考文献
Podzigun, G. I.; Pashkurov, N. G.; Reznik, V. S.; Ivanov, B. E.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1980 , vol. 29, p. 1662 - 1665
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1980 , # 10 p. 2346 - 2349
反应条件
sodium hydroxide in methanol; water
T=20°C; 1 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2009/22185 A2, 2009 ;
Location in patent: Page/Page column 25 ;
WO 2009/022185 A2
反应条件
dihydrogen peroxide; sodium hydroxide in water
T=0 - 20°C;
参考文献
Jungmann, Oliver; Pfleiderer, Wolfgang
Nucleosides, Nucleotides and Nucleic Acids, 2009 , vol. 28, # 5-7 p. 550 - 585
