2,4,5,6-四氨基嘧啶合成路线 (共 51 条)
反应条件
in water T=80°C; 3 h;
参考文献
Palanki, Moorthy S. S.; Dneprovskaia, Elena; Doukas, John; Fine, Richard M.; Hood, John; Kang, Xinshan; Lohse, Dan; Martin, Michael; Noronha, Glenn; Soll, Richard M.; Wrasidlo, Wolfgang; Yee, Shiyin; Zhu, Hong
Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4279 - 4294
反应条件
I2 Yield given. Multistep reaction;
参考文献
Rosowsky, Andre; Wright, Joel E.; Vaidya, Chitra M.; Forsch, Ronald A.; Bader, Henry
Journal of Medicinal Chemistry, 2000 , vol. 43, # 8 p. 1620 - 1634
反应条件
in wss.Loesung vom pH 3;
参考文献
Am.Cyanamid Co.
Patent: US2512572 , 1947 ;
反应条件
hydrogenchloride; sodium hydrogensulfite
参考文献
Mallette et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 1814
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Albert et al.
Journal of the Chemical Society, 1952 , p. 4219,4220
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Konrad; Pfleiderer
Chemische Berichte, 1970 , vol. 103, p. 722,729
反应条件
water; sodium hydrogensulfite
参考文献
Konrad; Pfleiderer
Chemische Berichte, 1970 , vol. 103, p. 722,729
参考文献
Spickett; Timmis
Journal of the Chemical Society, 1954 , p. 2887,2891
反应条件
hydrogenchloride; sodium hydrogensulfite
参考文献
Mallette et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 1814
参考文献
Mallette et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 1814
反应条件
hydrogenchloride; butanone
参考文献
Palanki, Moorthy S. S.; Dneprovskaia, Elena; Doukas, John; Fine, Richard M.; Hood, John; Kang, Xinshan; Lohse, Dan; Martin, Michael; Noronha, Glenn; Soll, Richard M.; Wrasidlo, Wolfgang; Yee, Shiyin; Zhu, Hong
Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4279 - 4294
反应条件
triethylamine
T=20°C; 240 h;
参考文献
Zav'yalov, S. I.; Zavozin, A. G.; Ezhova, G. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 11 p. 2183 - 2185
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 11 p. 2626 - 2628