反应条件
Multi-step reaction with 3 steps 1: 80 percent / 1N aq. NaOH / ethanol / 2 h / Ambient temperature2: 82 percent / N-hydroxysuccinimide, N,N'-dicyclohexylcarbodiimide, NH3 / tetrahydrofuran / Ambient temperature3: 46 percent / TFA / CH2Cl2 / 3 h / 0 - 20 °C
参考文献
Fournie-Zaluski; Lucas-Soroca; Devin; Roques Journal of medicinal chemistry, 1986 , vol. 29, # 5 p. 751 - 757