1-(4-氟苄基)-1H-苯并[d]咪唑-2(3H)-酮合成路线 （共 11 条）
反应条件
copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene in dimethyl sulfoxide T=140°C; 0.333333 h; Microwave irradiation;
参考文献
Li, Zhaoguang; Sun, Hongbin; Jiang, Hualiang; Liu, Hong
Organic Letters, 2008 , vol. 10, # 15 p. 3263 - 3266
反应条件
copper(l) iodide; N,N,N',N,-tetramethylethylenediamine in water T=120°C; 15 h;
参考文献
Barbero, Nekane; Carril, Monica; SanMartin, Raul; Dominguez, Esther
Tetrahedron, 2008 , vol. 64, # 30-31 p. 7283 - 7288
反应条件
1: xylene / 18 h / Heating 2: H2 / 10percent Pd/C / methanol / 4 h 3: CaCl2 / 1.5 h / 210 °C View Scheme
参考文献
Gomez-Parra, Vicente; Sanchez, Felix; Torres, Tomas
Monatshefte fuer Chemie, 1985 , vol. 116, p. 639 - 644
反应条件
1: H2 / 10percent Pd/C / methanol / 4 h 2: CaCl2 / 1.5 h / 210 °C View Scheme
参考文献
Gomez-Parra, Vicente; Sanchez, Felix; Torres, Tomas
Monatshefte fuer Chemie, 1985 , vol. 116, p. 639 - 644
反应条件
in N,N-dimethyl-formamide T=160°C; 5 h;
参考文献
Sasmal, Pradip K.; Sasmal, Sanjita; Rao, P. Tirumala; Venkatesham; Roshaiah; Abbineni, Chandrasekhar; Khanna, Ish; Jadhav, Vikram P.; Suresh; Talwar, Rashmi; Muzeeb, Syed; Receveur, Jean-Marie; Frimurer, Thomas M.; Rist, ystein; Elster, Lisbeth; Hoegberg, Thomas
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 18 p. 5443 - 5448
反应条件
sodium hydride 1.) DMF, 60 deh C, 1 h, 2.) DMF, 60 deg C, 5.5 h; Yield given. Multistep reaction;
参考文献
De Parrodi, Cecilia Anaya; Quintero-Cortes, Leticia; Sandoval-Ramirez, Jesus
Synthetic Communications, 1996 , vol. 26, # 17 p. 3323 - 3329
反应条件
lutidine; cesium fluoride in various solvent(s) T=120°C; Substitution; 3 h; Product distribution; Further Variations:ReagentsSolventsTemperaturespH-values;
参考文献
Senanayake, Chris H.; Hong, Yaping; Xiang, Tingjian; Scott Wilkinson; Bakale, Roger P.; Jurgens, Alex R.; Pippert, Mark F.; Butler, Hal T.; Wald, Stephen A.
Tetrahedron Letters, 1999 , vol. 40, # 38 p. 6875 - 6879
反应条件
trichlorophosphate 5.5 h; Heating;
参考文献
De Parrodi, Cecilia Anaya; Quintero-Cortes, Leticia; Sandoval-Ramirez, Jesus
Synthetic Communications, 1996 , vol. 26, # 17 p. 3323 - 3329
反应条件
1: 84 percent / phosphoryl chloride / 5.5 h / Heating 2: 56 percent / 5 h / 125 °C View Scheme
参考文献
De Parrodi, Cecilia Anaya; Quintero-Cortes, Leticia; Sandoval-Ramirez, Jesus
Synthetic Communications, 1996 , vol. 26, # 17 p. 3323 - 3329
反应条件
1: 84 percent / phosphoryl chloride / 5.5 h / Heating 2: 56 percent / 5 h / 125 °C 3: 95 percent / aq. HBr / 1 h / Heating 4: 1.) NaH, KI / 1.) DMF, 70 deg C, 10 h, 2.) DMF, 70 deg C, 12 h View Scheme
参考文献
De Parrodi, Cecilia Anaya; Quintero-Cortes, Leticia; Sandoval-Ramirez, Jesus
Synthetic Communications, 1996 , vol. 26, # 17 p. 3323 - 3329
