4,6-二氨基-2-甲基巯基嘧啶合成路线 （共 14 条）
反应条件
1: 2 h / 160 °C
2: 1 h / 150 °C
3: diphenylether / 0.67 h / 260 °C
View Scheme
参考文献
LYNDOR BIOSCIENCES L.L.C.; AKINSANMI, Lawrence; KINCAID, John
Patent: WO2012/158197 A2, 2012 ;
反应条件
in ethanol
T=135 - 165°C; 1.66667 h; Reflux; Product distribution / selectivity;
参考文献
LYNDOR BIOSCIENCES L.L.C.; AKINSANMI, Lawrence; KINCAID, John
Patent: WO2012/158197 A2, 2012 ;
Location in patent: Page/Page column 104-105 ;
参考文献
Anderson; Richardson
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 6 p. 1735 - 1737
反应条件
acetic acid; sodium nitrite
参考文献
Baddiley et al.
Journal of the Chemical Society, 1943 , p. 383,384
Journal of the Chemical Society, 1944 , p. 318,321
