5-溴-N-(2-甲氧基乙基)吡啶-2-胺合成路线 （共 2 条）
反应条件
N-ethyl-N,N-diisopropylamine in dimethyl sulfoxide T=180°C; 2 h;
参考文献
AMBIT BIOSCIENCES CORPORATION; ABRAHAM, Sunny; HOLLADAY, Mark, W.; LIU, Gang; XU, Shimin
Patent: WO2011/22473 A1, 2011 ;
Location in patent: Page/Page column 187-188 ;
WO 2011/022473 A1
反应条件
1: 5-bromopyridin-2-yl amine With sodium hydride in N,N-dimethyl-formamide T=0 - 5°C; Inert atmosphere; 2: 1-chloro-2-methoxy-ethane in N,N-dimethyl-formamide T=0°C; 0.833333 h;
参考文献
TAIVEX THERAPEUTICS CORPORATION; HUANG, Yu-Ling; CHUANG, Shih-Hsien; LEE, Ying-Shuan Eda; HUANG, Jiann-Jyh; LAU, Johnson
Patent: WO2013/82324 A1, 2013 ;
Location in patent: Paragraph 00196 ;
