in neat (no solvent) T=120°C; P=0.05 - 0.1 Torr; 2 h;

Multi-step reaction with 4 steps 1: tetrahydrofuran / -78 °C2: pyridine3: NaIO4 / methanol; H2O4: 1.) LDA; 2.) glacial acetic acid / 1.) THF, -78 to RT, 10 h; 2.) THF, RT, 1 h  

Multi-step reaction with 3 steps 1: pyridine2: NaIO4 / methanol; H2O3: 1.) LDA; 2.) glacial acetic acid / 1.) THF, -78 to RT, 10 h; 2.) THF, RT, 1 h