2-[(4-乙氧基-4-氧代丁基)(4-甲基苯磺酰基)氨基]苯甲酸甲酯合成路线 (共 7 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 18 h;
参考文献
FERRING B.V.
Patent: WO2006/21213 A2, 2006 ;
Location in patent: Page/Page column 32-33 ;
WO 2006/021213 A2
参考文献
GILEAD SCIENCES, INC.; MACKMAN, Richard, L.; SPERANDIO, David; YANG, Hai
Patent: WO2011/5842 A1, 2011 ;
WO 2011/005842 A1
参考文献
GILEAD SCIENCES, INC.; MACKMAN, Richard, L.; SPERANDIO, David; YANG, Hai
Patent: WO2011/5842 A1, 2011 ;
WO 2011/005842 A1
反应条件
1: 80 - 85 °C 2: Py View Scheme
参考文献
McCall,I. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 1126 - 1128
参考文献
McCall,I. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 1126 - 1128
反应条件
potassium tert-butylate; benzene Erwaermen des Reaktionsprodukts mit wss.-aethanol.Salzsaeure;
参考文献
GILEAD SCIENCES, INC.; MACKMAN, Richard, L.; SPERANDIO, David; YANG, Hai
Patent: WO2011/5842 A1, 2011 ;
Location in patent: Page/Page column 45-46 ;
WO 2011/005842 A1
反应条件
potassium tert-butylate in toluene
T=70°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/37796 A1, 2005 ;
Location in patent: Page/Page column 38 ;