100638-20-8合成路线

参考文献

GLAXO GROUP LIMITED; BERTANI, Barbara; CREMONESI, Susanna; GARZYA, Vincenzo; MICHELI, Fabrizio; RUPCIC, Renata; SABBATINI, Fabio Maria
Patent: WO2011/151361 A1, 2011 ;
Location in patent: Page/Page column 54-55 ;
WO 2011/151361 A1

105-39-5氯乙酸乙酯+

73011-24-2

100638-20-8

参考文献

Sawhney, S N; Sharma, P. K.; Bajaj, K; Gupta, A
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, p. 280 - 284

371-40-44-氟苯胺

100638-20-8

参考文献

GLAXO GROUP LIMITED; BERTANI, Barbara; CREMONESI, Susanna; GARZYA, Vincenzo; MICHELI, Fabrizio; RUPCIC, Renata; SABBATINI, Fabio Maria
Patent: WO2011/151361 A1, 2011 ;
WO 2011/151361 A1

348-40-32-氨基-6-氟苯并噻唑

100638-20-8

参考文献

GLAXO GROUP LIMITED; BERTANI, Barbara; CREMONESI, Susanna; GARZYA, Vincenzo; MICHELI, Fabrizio; RUPCIC, Renata; SABBATINI, Fabio Maria
Patent: WO2011/151361 A1, 2011 ;
WO 2011/151361 A1

348-40-32-氨基-6-氟苯并噻唑+

79-11-8氯乙酸

100638-20-8

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Cecchetti, Violetta; Fravolini, Arnaldo; Fringuelli, Renata; Mascellani, Giuseppe; Pagella, Piergiuseppe; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 3 p. 465 - 473