8-甲酰基-1,4-二噁螺[4.5]癸烷-8-羧酸乙酯合成路线 (共 1 条)
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78 - 20°C; Swern Oxidation; 1.5 h; 2: With water; ammonium chloride in dichloromethane
参考文献
Amgen Inc.
Patent: US2007/299080 A1, 2007 ;
Location in patent: Page/Page column 61-62 ;