1: 2.) HCl / 1.) from 135 deg C to 140 deg C, 2.) 90 deg C 2: glacial acetic acid / 1 h / Ambient temperature View Scheme
参考文献
Lanza, Thomas J.; Durette, Philippe L.; Rollins, Thomas; Siciliano, Salvatore; Cianciarulo, Dana N.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 252 - 258
1: 2.) HCl / 1.) from 135 deg C to 140 deg C, 2.) 90 deg C
2: glacial acetic acid / 1 h / Ambient temperature
View Scheme
参考文献
Lanza, Thomas J.; Durette, Philippe L.; Rollins, Thomas; Siciliano, Salvatore; Cianciarulo, Dana N.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 252 - 258
1: AcONH4 / 4 h / 135 °C
2: aq. HCl / 5 h / 90 °C
3: pyridine / 3 h / 20 °C
View Scheme
参考文献
Lanza, Thomas J.; Durette, Philippe L.; Rollins, Thomas; Siciliano, Salvatore; Cianciarulo, Dana N.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 252 - 258
