7-氯-1H-吲哚-3-苯甲醛合成路线 (共 3 条)
反应条件
trichlorophosphate in diethyl ether; N,N-dimethyl-formamide T=20°C; 2 h;
参考文献
Brigham and Women's Hospital, Inc.; President and Fellows of Harvard College
Patent: US2005/119260 A1, 2005 ;
Location in patent: Page/Page column 36 ;
参考文献
WO2007/75772 A2, ;
Page/Page column 124 ;
反应条件
1: piperidine; acetic acid / benzene / Reflux
2: lithium aluminium tetrahydride / tetrahydrofuran / Reflux
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参考文献
Nirogi, Ramakrishna V.S.; Kambhampati, Ramasastri; Kothmirkar, Prabhakar; Konda, Jagadishbabu; Bandyala, Thrinath Reddy; Gudla, Parandhama; Arepalli, Sobhanadri; Gangadasari, Narasimhareddy P.; Shinde, Anil K.; Deshpande, Amol D.; Dwarampudi, Adireddy; Chindhe, Anil K.; Dubey, Pramod Kumar
Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 3 p. 443 - 450