2,4-二氢-4-苯基-3H-1,2,4-噻唑-3-酮合成路线 （共 7 条）
反应条件
acetic acid in N,N-dimethyl-formamide T=80°C; 8 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 11 p. 5276 - 5282
反应条件
trifluorormethanesulfonic acid in toluene T=150°C; 0.25 h; Microwave irradiation;
参考文献
Rombouts, Frederik; Franken, Dennis; Martinez-Lamenca, Carolina; Braeken, Mirielle; Zavattaro, Chiara; Chen, Jinsheng; Trabanco, Andres A.
Tetrahedron Letters, 2010 , vol. 51, # 37 p. 4815 - 4818
反应条件
1: in ethanol T=50°C; 2: With sodium methylate in methanol; ethanol T=75°C;
参考文献
Shao, Ning; Wang, Cheng; Huang, Xianhai; Xiao, Dong; Palani, Anandan; Aslanian, Robert; Shih, Neng-Yang
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6743 - 6746
反应条件
1: in methanol 2 h; Reflux; 2: With sodium methylate in methanol 3 h; Reflux; 3: With hydrogenchloride in water pH=1;
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 3135 - 3141
反应条件
ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane T=140°C; 8 h;
参考文献
Hrebabecky, Hubert; Beranek, Jiri
Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 2 p. 779 - 788
反应条件
sodium hydroxide 12 h; Heating;
参考文献
Dobosz, Maria; Struga, Marta
Acta Poloniae Pharmaceutica - Drug Research, 1997 , vol. 54, # 4 p. 313 - 318
反应条件
1: 81 percent / formic acid / CH2Cl2 / 3 h / 20 °C 2: 58 percent / hexamethyldisilazane, ammonium sulfate / 8 h / 140 °C View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 50, # 2 p. 779 - 788
