5-甲基-3-苯基异噁唑合成路线 （共 67 条）
反应条件
1: 69 percent / iso-cyanatobenzene, triethylamine / benzene / Ambient temperature 2: lithium aluminium hydride View Scheme
参考文献
Brown, Roger S.; Eyley, Stephen C.; Parsons, Philip J.
Synthetic Communications, 1985 , vol. 15, # 7 p. 633 - 642
反应条件
1: diethyl ether / Heating 2: Zn / ethanol / Heating View Scheme
参考文献
Stagno d'Alcontres,G.; Lo Vecchio,G.
Gazzetta Chimica Italiana, 1960 , vol. 90, p. 1239 - 1252
反应条件
zinc in ethanol Heating;
参考文献
Stagno d'Alcontres,G.; Lo Vecchio,G.
Gazzetta Chimica Italiana, 1960 , vol. 90, p. 1239 - 1252
反应条件
in benzene T=200°C; 26 h;
参考文献
Maeda,M.; Kojima,M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 239 - 247
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -30 to -25 deg C, 90 min, 2.) THF, -30 to -25 deg C, 2 h 2: 1 N HCl / 3 h / Heating 3: 77 percent / NH2OH*HCl / H2O; ethanol / 24 h / 140 °C / bomb tube 4: 75 percent / 2 N NaOH / H2O / 1 h / Ambient temperature View Scheme
参考文献
Oehler, Elisabeth; Zbiral, Erich
Chemische Berichte, 1980 , vol. 113, # 9 p. 2852 - 2867
反应条件
1: 1 N HCl / 3 h / Heating 2: 77 percent / NH2OH*HCl / H2O; ethanol / 24 h / 140 °C / bomb tube 3: 75 percent / 2 N NaOH / H2O / 1 h / Ambient temperature View Scheme
参考文献
Oehler, Elisabeth; Zbiral, Erich
Chemische Berichte, 1980 , vol. 113, # 9 p. 2852 - 2867
反应条件
1: 77 percent / NH2OH*HCl / H2O; ethanol / 24 h / 140 °C / bomb tube 2: 75 percent / 2 N NaOH / H2O / 1 h / Ambient temperature View Scheme
参考文献
Oehler, Elisabeth; Zbiral, Erich
Chemische Berichte, 1980 , vol. 113, # 9 p. 2852 - 2867
反应条件
1: 93 percent / NH2OH*HCl, 10percent aqueous sodium hydroxide / ethanol / 0.33 h / Heating 2: 96 percent / disodium hydrogenphosphate, 5percent sodium amalgam / methanol / 2 h View Scheme
参考文献
Yokoyama, Masataka; Tsuji, Kouichi; Kushida, Mari
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 67 - 72
反应条件
1: 72 percent / t-BuOK, CuI / tetrahydrofuran / 15 h 2: 93 percent / NH2OH*HCl, 10percent aqueous sodium hydroxide / ethanol / 0.33 h / Heating 3: 96 percent / disodium hydrogenphosphate, 5percent sodium amalgam / methanol / 2 h View Scheme
参考文献
Yokoyama, Masataka; Tsuji, Kouichi; Kushida, Mari
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 67 - 72
反应条件
1: (i) Et3N, CHCl3, (ii) aq. HCl 2: Cu / quinoline / Heating View Scheme
参考文献
Bianchetti,G. et al.
Gazzetta Chimica Italiana, 1963 , vol. 93, p. 1714 - 1725
