5-溴-6-氟-1H-苯并咪唑合成路线 （共 3 条）
参考文献
F. HOFFMANN-LA ROCHE AG; ALIAGAS-MARTIN, Ignacio; CRAWFORD, James; LEE, Wendy; MATHIEU, Simon; RUDOLPH, Joachim
Patent: WO2013/26914 A1, 2013 ;
Location in patent: Page/Page column 134 ;
WO 2013/026914 A1
反应条件
1: acetic acid; N-bromosuccinmide / 1.5 h / |Reflux 2: tin(ll) chloride / ethanol / 14 h / |Reflux 3: |Reflux View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; ALIAGAS-MARTIN, Ignacio; CRAWFORD, James; LEE, Wendy; MATHIEU, Simon; RUDOLPH, Joachim
Patent: WO2013/26914 A1, 2013 ;
WO 2013/026914 A1
反应条件
1: tin(ll) chloride / ethanol / 14 h / |Reflux 2: |Reflux View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; ALIAGAS-MARTIN, Ignacio; CRAWFORD, James; LEE, Wendy; MATHIEU, Simon; RUDOLPH, Joachim
Patent: WO2013/26914 A1, 2013 ;
WO 2013/026914 A1
