5,5'-二氯-2,2'-联吡啶合成路线 （共 6 条）
反应条件
1: 3-chloropyridinetrifluoroborate With lithium diisopropyl amide in diethyl ether T=-78°C; Inert atmosphere; 2: 3-chloro-pyridine in diethyl ether T=-78°C; Inert atmosphere; 3: With water
参考文献
Dhau, Jaspreet S.; Singh, Amritpal; Kasetti, Yoganjaneyulu; Bhatia, Sonam; Bharatam, Parsad V.; Brandao, Paula; Felix, Vitor; Singh, Kamal N.
Tetrahedron, 2013 , vol. 69, # 48 p. 10284 - 10291
反应条件
NiII chloride hexahydrate; iodine; acetic acid; lithium chloride; zinc in N,N-dimethyl-formamide T=50 - 60°C; 6 h;
参考文献
Liao, Lian-Yan; Kong, Xing-Rui; Duan, Xin-Fang
Journal of Organic Chemistry, 2014 , vol. 79, # 2 p. 777 - 782
反应条件
1: With lithium diisopropyl amide in diethyl ether T=-78°C; Inert atmosphere; 2: With dimethyl-disulfide in diethyl ether Inert atmosphere; 3: With water
参考文献
Dhau, Jaspreet S.; Singh, Amritpal; Kasetti, Yoganjaneyulu; Bhatia, Sonam; Bharatam, Parsad V.; Brandao, Paula; Felix, Vitor; Singh, Kamal N.
Tetrahedron, 2013 , vol. 69, # 48 p. 10284 - 10291
反应条件
1: 92 percent 2: 65 percent / 30percent hydrogen peroxide / acetic acid / 24 h 3: 40 percent / EtMgBr / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Oae, Shigeru; Kawai, Tsutomu; Furukawa, Naomichi
Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 123 - 132
反应条件
1: 65 percent / 30percent hydrogen peroxide / acetic acid / 24 h 2: 40 percent / EtMgBr / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Oae, Shigeru; Kawai, Tsutomu; Furukawa, Naomichi
Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 123 - 132
反应条件
1.1: diethyl ether / 0 °C / |Inert atmosphere 2.1: lithium diisopropyl amide / diethyl ether / -78 °C / |Inert atmosphere 2.2: |Inert atmosphere View Scheme
参考文献
Dhau, Jaspreet S.; Singh, Amritpal; Kasetti, Yoganjaneyulu; Bhatia, Sonam; Bharatam, Parsad V.; Brandao, Paula; Felix, Vitor; Singh, Kamal N.
Tetrahedron, 2013 , vol. 69, # 48 p. 10284 - 10291
