2-吡啶-4-基-1-对甲苯乙酮合成路线 （共 7 条）
反应条件
1: 4-Methylpyridine With lithium diisopropyl amide in tetrahydrofuran; hexane T=-10°C; 0.333333 h; 2: 1-(4-methylbenzoyl)-2-methylaziridine in tetrahydrofuran; hexane T=-78°C; 1 h;
参考文献
Miwatashi, Seiji; Arikawa, Yasuyoshi; Naruo, Ken-Ichi; Igaki, Keiko; Watanabe, Yasumasa; Kimura, Hiroyuki; Kawamoto, Tomohiro; Ohkawa, Shigenori
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 4 p. 410 - 418
反应条件
1: 4-Methylpyridine With lithium hexamethyldisilazane T=0°C; 0.5 h; 2: 4-methyl-benzoic acid methyl ester
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 8 p. 2634 - 2638
反应条件
water; hydrogen bromide T=170°C;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 600, p. 176,188
反应条件
1.1: 91 percent / aq. NaOH / diethyl ether / 0 °C 2.1: LDA / tetrahydrofuran; hexane / 0.33 h / -10 °C 2.2: 70 percent / tetrahydrofuran; hexane / 1 h / -78 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 53, # 4 p. 410 - 418
反应条件
Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 112, # 8 p. 3163 - 3168
反应条件
1: methanol; N,N-dimethyl-4-nitroso-aniline; NaOH-solution / Reagens 4:Wasser ;unter Stickstoff 2: hydrobromic acid; water / 170 °C View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 600, p. 176,188
反应条件
1: methanol; N,N-dimethyl-4-nitroso-aniline; NaOH-solution / Reagens 4:Wasser ;unter Stickstoff 2: hydrobromic acid; water / 170 °C View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 600, p. 176,188
