((1R,2R)-2-羟基-1-羟甲基-2-苯基乙基)氨基甲酸叔丁酯合成路线 （共 9 条）
参考文献
Infinity Discovery, Inc.
Patent: US2008/114167 A1, 2008 ;
Location in patent: Page/Page column 152 ;
US 20080114167 A1
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=0 - 25°C;
参考文献
Veeresa; Datta, Apurba
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8503 - 8004
反应条件
1: 1.) (COCl)2, DMSO, i-Pr2NEt / 1.) CH2Cl2, -78 deg C, 2.) THF, room temp. 2: Bu4NF / tetrahydrofuran / 0 - 25 °C View Scheme
参考文献
Veeresa; Datta, Apurba
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8503 - 8004
反应条件
1: 1.) (COCl)2, DMSO, i-Pr2NEt / 1.) CH2Cl2, -78 deg C, 2.) THF, room temp. 2: Bu4NF / tetrahydrofuran / 0 - 25 °C View Scheme
参考文献
Veeresa; Datta, Apurba
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8503 - 8004
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 1 h / 20 °C 2: lithium hydroxide hydrate / water; 1,4-dioxane / 4 h / 20 °C View Scheme
参考文献
Liu, Guan-Sai; Zhang, Yong-Qiang; Yuan, Yong-An; Xu, Hao
Journal of the American Chemical Society, 2013 , vol. 135, # 9 p. 3343 - 3346
反应条件
1: DMAP / pyridine 2: F3CCO2H / 0 °C 3: DMAP / pyridine 4: conc. HNO3, conc. H2SO4 / -20 - 25 °C 5: aq. HCl / 90 °C View Scheme
参考文献
Veeresa; Datta, Apurba
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8503 - 8004
反应条件
1: DMAP / pyridine 2: F3CCO2H / 0 °C 3: DMAP / pyridine 4: conc. HNO3, conc. H2SO4 / -20 - 25 °C 5: aq. HCl / 90 °C View Scheme
参考文献
Veeresa; Datta, Apurba
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8503 - 8004
反应条件
1: DMAP / pyridine 2: F3CCO2H / 0 °C 3: DMAP / pyridine 4: conc. HNO3, conc. H2SO4 / -20 - 25 °C 5: aq. HCl / 90 °C 6: 73 percent / 90 °C View Scheme
参考文献
Veeresa; Datta, Apurba
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8503 - 8004
反应条件
1: DMAP / pyridine 2: F3CCO2H / 0 °C 3: DMAP / pyridine 4: conc. HNO3, conc. H2SO4 / -20 - 25 °C 5: aq. HCl / 90 °C View Scheme
参考文献
Veeresa; Datta, Apurba
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8503 - 8004
