4-(乙酰基氨基)-3-羟基苯甲酸合成路线 (共 4 条)
反应条件
1: With methanol; potassium hydroxide; water in tetrahydrofuran T=20°C; 1.08333 h; 2: With hydrogenchloride in tetrahydrofuran; methanol; water pH=2.5;
参考文献
METHYLGENE INC.
Patent: WO2007/118137 A1, 2007 ;
Location in patent: Page/Page column 109 ;
反应条件
sodium hydroxide 0.5 h; Ambient temperature;
参考文献
The University of Alabama at Birmingham
Patent: US5453533 A1, 1995 ;
US 5453533 A
反应条件
hydrogenchloride; tin Behandeln einer wss. Loesung des Reaktionsprodukts mit Acetanhydrid;
参考文献
Kasuya; Igarashi; Fukui
Journal of Pharmaceutical Sciences, 1987 , vol. 76, # 4 p. 303 - 305
反应条件
1 h; Ambient temperature;
参考文献
Kasuya; Igarashi; Fukui
Journal of Pharmaceutical Sciences, 1987 , vol. 76, # 4 p. 303 - 305