4,4'-二氨基二苯甲烷合成路线 （共 194 条）
反应条件
hydrogen; 5 ruthenium/lithium aluminate in tetrahydrofuran T=180 - 190°C; P=41372.9 - 43958.7 Torr; 12 h; Product distribution / selectivity;
参考文献
Air Products and Chemicals, Inc.
Patent: EP1767520 A1, 2007 ;
Location in patent: Page/Page column 11 ;
反应条件
hydrogen; 5 wt. ruthenium on carbon in methanol T=160°C; P=30003 - 45004.5 Torr; 2.5 h; Industry scale; Product distribution / selectivity;
参考文献
Ningbo Wanhua Polyurethanes Co., Ltd.; Yantai Wanhua Polyurethanes Co., Ltd.
Patent: EP2502900 A1, 2012 ;
Location in patent: Page/Page column 8 ;
反应条件
hydrogen; 5 Ru/Al2O3 in tetrahydrofuran T=83 - 105°C;
参考文献
DEGUSSA AG
Patent: WO2004/7425 A2, 2004 ;
Location in patent: Page 9-12 ;
反应条件
hydrogen; 5 Ru/Al2O3 in tetrahydrofuran T=90 - 110°C;
参考文献
DEGUSSA AG
Patent: WO2004/7425 A2, 2004 ;
Location in patent: Page 9-12 ;
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane 40 h; Heating;
参考文献
Halton, Brian; Lu, Qi; Stang, Peter J.
Australian Journal of Chemistry, 1990 , vol. 43, # 7 p. 1277 - 1282
参考文献
Barclay; Burawoy; Thomson
Journal of the Chemical Society, 1944 , p. 109,111
反应条件
sodium hydroxide in water
T=20°C; 4 h; Inert atmosphere;
参考文献
Fung, Yuen On; Wu, Wanqing; Yeung, Chi-Tung; Kong, Hoi-Kuan; Wong, Kenny Kam-Cheng; Lo, Wai-Sum; Law, Ga-Lai; Wong, Ka-Leung; Lau, Chi-Kong; Lee, Chi-Sing; Wong, Wing-Tak
Inorganic Chemistry, 2011 , vol. 50, # 12 p. 5517 - 5525
反应条件
2: nitric acid / -5 - 0 °C
3: KOH-solution
View Scheme
参考文献
Butler; Adams
Journal of the American Chemical Society, 1925 , vol. 47, p. 2615
反应条件
1: With 3-chloro-benzenecarboperoxoic acid in 1,2-dichloro-ethane
2: With chromium(VI) oxide in acetic acid
参考文献
Wu, Yi-Lin; Bures, Filip; Jarowski, Peter D.; Schweizer, W. Bernd; Boudon, Corinne; Gisselbrecht, Jean-Paul; Diederich, Francois
Chemistry - A European Journal, 2010 , vol. 16, # 31 p. 9592 - 9605
反应条件
1.1: isopentyl nitrite; HCO2H / 0 - 5 °C
2.1: NaOMe / methanol
2.2: 91 percent / methanol / 0.5 h / 20 - 25 °C
3.1: 82 percent / diethyl ether / 0.42 h / 0 - 25 °C
View Scheme
参考文献
Kimura, Tsutomu; Hosokawa-Muto, Junji; Kamatari, Yuji O.; Kuwata, Kazuo
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 5 p. 1502 - 1507
