4,4'-二氨基二苯甲烷合成路线 （共 194 条）
反应条件
Wyoming bentonite; water; aniline
T=180°C; 2 h; MechanismProduct distribution;
参考文献
Whitman, Peter J.; Frulla, Floro F.; Temme, George H.; Stuber, Fred A.
Tetrahedron Letters, 1986 , vol. 27, # 17 p. 1887 - 1890
反应条件
1: 40 percent / HCl / ethanol
2: 80 percent / m-CPBA / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Schuetze, Dietrich; Sagelsdorff, Peter; Sepai, Ovnair; Sabbioni, Gabriele
Chemical Research in Toxicology, 1996 , vol. 9, # 7 p. 1103 - 1112
反应条件
hydrogen; Pt(S)/C in toluene
T=22 - 60°C; P=6448.83 Torr; 2 h; Autoclave; Product distribution / selectivity;
参考文献
Lee, John Y.; Wiggins, Paul L.; Orgad, Judith O.; Sabahi, Mahmood; Brandt, Vernon O.
Patent: US2006/217567 A1, 2006 ;
Location in patent: Page/Page column 16 ;
反应条件
1: in methanol
0.166667 h;
2: With acetic acid in methanol
2 h; Heating / reflux;
参考文献
UNIVERSITY OF WARWICK
Patent: WO2005/33119 A1, 2005 ;
Location in patent: Page/Page column 38 ;
反应条件
in dichloromethane
T=20°C; Schlenk techniqueInert atmosphere;
参考文献
Pichon, Benoet P.; Scampini, Sylvana; Bied, Catherine; Moreau, Joel J. E.; Wong Chi Man, Michel
European Journal of Inorganic Chemistry, 2012 , # 32 p. 5312 - 5322
反应条件
potassium carbonate; butan-1-ol
参考文献
Goodson et al.
British Journal of Pharmacology and Chemotherapy, 1948 , vol. 3, p. 61
Chem.Abstr., 1949 , p. 3380
参考文献
Am. Cyanamid Co.
Patent: US2544071 , 1947 ;
反应条件
N-benzyl-N,N,N-triethylammonium chloride in sodium hydroxide; dichloromethane
Hofmann carbylamine reaction;
参考文献
Morel, Georges; Marchand, Evelyne; Sinbandhit, Sourisak; Carlier, Roger
European Journal of Organic Chemistry, 2001 , # 4 p. 655 - 662
反应条件
1: 12 h / |Reflux
2: bis(trichloromethyl) carbonate; triethylamine / dichloromethane / 3 h / 0 °C / |Reflux
View Scheme
参考文献
Liang, Jinhua; Hu, Fang; Lv, Xiaoyi; Chen, Zhao; Chen, Zhiming; Yin, Jun; Yu, Guang-Ao; Liu, Sheng Hua
Dyes and Pigments, 2012 , vol. 95, # 3 p. 485 - 490
反应条件
2: tin; HCl / 135 - 140 °C
3: sulfuric acid / 195 °C
View Scheme
参考文献
Benda
Chemische Berichte, 1912 , vol. 45, p. 1796
