2-丁基-2-乙基-3-羟基丙酸合成路线 (共 3 条)
反应条件
sodium periodate; tetrabutyl ammonium fluoride; RuCl3 in tetrahydrofuran; tetrachloromethane
参考文献
Glaxo Wellcome Inc.
Patent: US5998400 A1, 1999 ;
反应条件
1: 2-ethyl-1-hexanoic acid With n-butyllithium; diisopropylamine in tetrahydrofuran; n-heptane T=0 - 50°C; 2.16667 h; 2: formaldehyd in tetrahydrofuran; n-heptane T=0 - 20°C; 18.1667 h; 3: With hydrogenchloride; water; ammonium chloride in tetrahydrofuran; n-heptane pH=1 - 2; Product distribution / selectivity;
参考文献
Consortium fuer elektrochemische Industrie GmbH
Patent: EP1666447 A1, 2006 ;
Location in patent: Page/Page column 7 ;
反应条件
potassium permanganate
参考文献
SANOFI-AVENTIS DEUTSCHLAND GMBH
Patent: US2011/245486 A1, 2011 ;
Location in patent: Page/Page column 16 ;