2,6-二氯吡啶-3,4-二胺合成路线 （共 16 条）
反应条件
1: 5 h / 145 °C 2: formic acid / 5 h / 110 °C View Scheme
参考文献
Bande, Omprakash; Herdewijn, Piet
European Journal of Organic Chemistry, 2014 , vol. 2014, # 1 p. 231 - 236
参考文献
Seley, Katherine L.; O'Daniel, Peter I.; Salima, Samer
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 12 p. 2133 - 2144
参考文献
MERCK and CO., INC.
Patent: WO2006/31491 A2, 2006 ;
Location in patent: Page/Page column 42; 79 ;
WO 2006/031491 A2
反应条件
1: 38 percent / 72 h / Heating
2: 49 percent / aq. KOH / Heating
View Scheme
参考文献
Seley, Katherine L.; O'Daniel, Peter I.; Salima, Samer
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 12 p. 2133 - 2144
反应条件
hydrogenchloride; sodium nitrite in water
T=0°C; 0.0833333 h;
参考文献
Wright, George E.; Xu, Wei-Chu; Brown, Neal C.
Patent: US2004/14773 A1, 2004 ;
Location in patent: Page/Page column 10; 13 ;
反应条件
1: 96 percent / Ac2O / 4.5 h / Heating
2: 49 percent / ammonia / methanol / 90 h / 160 °C
View Scheme
参考文献
Seley, Katherine L.; O'Daniel, Peter I.; Salima, Samer
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 12 p. 2133 - 2144
