1-(喹啉-2-基)乙酮合成路线 (共 46 条)
反应条件
1: 83 percent / propan-2-ol / 2 h / Heating
2: 90 percent / methanol / 8 h / Heating
View Scheme
参考文献
Klayman; Scovill; Bartosevich; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 1 p. 49 - 53
反应条件
1: 83 percent / propan-2-ol / 2 h / Heating
2: 24 percent / methanol / 8 h / Heating
View Scheme
参考文献
Klayman; Scovill; Bartosevich; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 1 p. 49 - 53
反应条件
1: 83 percent / propan-2-ol / 2 h / Heating
2: 80 percent / methanol / 8 h / Heating
3: 89 percent / sodium borohydride
View Scheme
参考文献
Klayman; Scovill; Bartosevich; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 1 p. 49 - 53
反应条件
1: 83 percent / propan-2-ol / 2 h / Heating
2: 75 percent / 1) sodium borohydride, 2) glacial acetic acid, H2O / ethanol / 1.5 h
3: 59 percent
View Scheme
参考文献
Klayman; Scovill; Bartosevich; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 1 p. 49 - 53
反应条件
potassium hydroxide in N,N-dimethyl-formamide
6 h; Ambient temperature;
参考文献
Tominaga, Yoshinori; Ushirogochi, Atsuyuki; Matsuda, Yoshiro; Kobayashi, Goro
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 9 p. 3384 - 3395
参考文献
Case; Maerker
Journal of the American Chemical Society, 1953 , vol. 75, p. 4920